Usually Santa Fe de la Vera Cruz is just called Santa Fe. It is the capital city of the province by the same name. The city has a population of 405,000 people. This is about the size of Minneapolis, Minnesota. Santa Fe was established first as a settlement in 1573, but was moved to its current location in 1653 due to flooding. It sits in a humid subcultural climate, and is the center of a large agricultural area.
Historically the city has been the site of Constitutional Conventions in 1949, 1957, and 1994. It is also the burial place of Hernando Arias de Saavedra, who was the first South American-born person to become a governor of an European Colony.
Santa Fe has a port that is one of the most inland ports in the world. It sits some 250 miles away from Rio de la Plata, and handles commerce and trade for Bolivia and Paraguay.
I know of at least one Baptist church that is located in the city. Pray for them there that God would bless their ministry, and that more might be started.